I'm a Gibson man, myself, but the G-5A VG Stratocaster from Roland and Fender is very interesting. It has on-board processing that gives you access to 25 different tones, from a classic Strat, to a Tele, to an acoustic guitar, to a 12-string, and more, all without changing your guitar or mucking about with pedals. This is an American-made Fender, while the on-board effects are from Roland. You can bypass the effects and play it like a normal analog Strat, too.
Check It Out: Roland G-5A VG Stratocaster